A pragmatic view on pragmatic trials.

Nikolaos A Patsopoulos1

  • 1Division of Genetics, Department of Medicine, Brigham & Women's Hospital, Harvard Medical School, 77 Avenue Louis Pasteur, New Research Building (NRB) #150 Boston, MA 02115, USA. npatsopoulos@rics.bwh.harvard.edu

Summary

Pragmatic clinical trials are increasingly favored for evaluating interventions in real-world settings, offering generalizable results. This review explores the pragmatic design, its continuum with explanatory trials, and its impact on medical practice.

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