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Updated: May 30, 2026

Isolation of Brain-infiltrating Leukocytes
Published on: June 13, 2011
[A brain abscess as a complication of hepatopulmonary syndrome coexisting with interstitial pneumonia]
Toyoshi Yanagihara1, Atsushi Moriwaki, Nanae Seki
1Nippon Steel Yawata Memorial Hospital.
Abstract:
A 76-year-old woman with a 20-year history of chronic hepatitis C was referred to our hospital for worsening exertional dyspnea. She had been given a diagnosis of interstitial pneumonia based on chest computed tomography findings 5 years previously. Contrast-enhanced echocardiography confirmed an intrapulmonary right-to-left shunt, and therefore we diagnosed hepatopulmonary syndrome comorbid with interstitial pneumonia. In July 2009 she was admitted to our hospital with a low grade fever, headache, and vomiting. We diagnosed a left cerebellar brain abscess caused by Streptococcus intermedius. She underwent stereotactic burr-hole drainage and received vancomycin, piperacillin and cefotaxime. Cases of brain abscess secondary to hepatopulmonary syndrome are rare. Nevertheless, we should be aware of this complication of hepatopulmonary syndrome.
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