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Updated: May 30, 2026

Cultivation Methods of Spirochetes from Borrelia burgdorferi Sensu Lato Complex and Relapsing Fever Borrelia
Published on: November 25, 2022
Population genetics, taxonomy, phylogeny and evolution of Borrelia burgdorferi sensu lato
Gabriele Margos1, Stephanie A Vollmer, Nicholas H Ogden
1Department of Biology and Biochemistry, University of Bath, Claverton Down, Bath BA2 7AY, UK. gm250@bath.ac.uk
Abstract:
In order to understand the population structure and dynamics of bacterial microorganisms, typing systems that accurately reflect the phylogenetic and evolutionary relationship of the agents are required. Over the past 15 years multilocus sequence typing schemes have replaced single locus approaches, giving novel insights into phylogenetic and evolutionary relationships of many bacterial species and facilitating taxonomy. Since 2004, several schemes using multiple loci have been developed to better understand the taxonomy, phylogeny and evolution of Lyme borreliosis spirochetes and in this paper we have reviewed and summarized the progress that has been made for this important group of vector-borne zoonotic bacteria.
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