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Related Experiment Video

Updated: May 30, 2026

An Affordable HIV-1 Drug Resistance Monitoring Method for Resource Limited Settings

An Affordable HIV-1 Drug Resistance Monitoring Method for Resource Limited Settings

Published on: March 30, 2014

Adherence to dual-method contraceptive use.

Jeffrey F Peipert¹, Qiuhong Zhao, Laura Meints

¹Division of Clinical Research, Department of Obstetrics and Gynecology, Washington University in St. Louis School of Medicine, St. Louis, MO 63110, USA.

|August 17, 2011

Summary

This summary is machine-generated.

Sustained dual-method contraceptive use remains low, with only 9% of participants achieving it. Education and increased contraceptive stage of change were linked to better adherence, while substance abuse and no baseline contraceptive use were linked to lower adherence.

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Area of Science:

Reproductive Health
Contraception
Public Health Interventions

Background:

Patient characteristics influencing dual-method contraceptive adherence are not well understood.
Dual-method contraception combines methods (e.g., condoms with hormonal or long-acting reversible contraceptives) for enhanced protection.
Consistent and sustained dual-method use is crucial for preventing sexually transmitted diseases and unplanned pregnancies.

Purpose of the Study:

To identify patient characteristics associated with sustained dual-method contraceptive use.
To evaluate the effectiveness of an individualized computer-based intervention versus enhanced standard care in promoting dual-method use.

Main Methods:

A 24-month randomized trial (Project PROTECT) involving 463 women with follow-up data.
Intervention groups received either a computer-based program or enhanced standard care counseling.
Sustained dual-method use was defined as reporting use at two or more interviews.

Main Results:

While 32% initiated dual-method use, only 9% achieved sustained use.
Higher education (RR(adj)=4.42) and increased contraceptive stage of change (RR(adj)=5.04) were associated with sustained dual-method use.
Decreased substance abuse (RR(adj)=0.49) and no contraceptive use at baseline (RR(adj)=0.32) were also associated with improved adherence.

Conclusions:

Sustained dual-method contraceptive use is challenging but vital for disease and pregnancy prevention.
Future interventions should target high-risk populations and explore novel dual-method combinations (e.g., barrier methods with IUDs or implants).