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Ionized calcium: pediatric perspective.

R E Lynch1

  • 1Pediatric Intensive Care Unit, Cardinal Glennon Children's Hospital, St. Louis, Missouri.

Pediatric Clinics of North America
|April 1, 1990
PubMed
Summary
This summary is machine-generated.

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Directly measured ionized calcium is crucial for critically ill patients, especially neonates and those with cardiovascular instability. Accurate ionized calcium measurement is vital for diagnosis and research in various clinical settings.

Area of Science:

  • Biochemistry
  • Clinical Medicine

Background:

  • Ionized calcium is a critical physiological calcium pool.
  • Accurate measurement of ionized calcium is essential, particularly in specific patient populations.
  • Disturbances in calcium levels occur in numerous clinical scenarios.

Purpose of the Study:

  • To highlight the clinical significance of directly measured ionized calcium.
  • To emphasize the importance of accurate measurement techniques.
  • To discuss current and future applications of ionized calcium determination.

Main Methods:

  • Direct measurement of ionized calcium.
  • Review of clinical applications and technological capabilities.

Main Results:

Related Experiment Videos

  • Ionized calcium is a key parameter in neonates, sepsis, cardiovascular instability, massive transfusion, cardiopulmonary bypass, and liver transplantation.
  • Accurate diagnosis and research rely on the best available measurement methods.
  • Conclusions:

    • Clinical and investigational use of ionized calcium determinations are appropriate applications of current technology.
    • Future research may focus on transmembrane transport and intracellular calcium pools.
    • Current understanding is largely limited to extracellular calcium, with ongoing research into its complexities.