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Hormonal hyperthermia: endocrinologic causes of fever
The American Journal of Medicine
|February 1, 1979
Summary
Fever can be an unusual sign of endocrine diseases. This study identified six patients whose unexplained fevers were caused by hormonal imbalances, not infections.
Area of Science:
- Endocrinology
- Thermoregulation
Background:
- Fever is a common symptom of infection.
- Endocrine diseases rarely present with fever.
Observation:
- Six patients hospitalized for fever were found to have endocrine disorders.
- Initial diagnoses included tuberculosis, bacteremia, and endocarditis.
Findings:
- Infection was ruled out in all cases.
- Fever was attributed to thyrotoxicosis, T3 toxicosis, subacute thyroiditis, adrenal insufficiency, and pheochromocytoma.
- A seventh patient experienced extreme fever during thyroid storm.
Implications:
- Hormonal imbalances can manifest as unexplained fever.
- Physicians should consider endocrine disorders in patients with persistent fever of unknown origin.
- Understanding hormonal roles in thermoregulation is crucial for diagnosis.