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Adverse antibiotic effects associated with renal insufficiency.
F A Manian1, W J Stone, R H Alford
1Division of Infectious Diseases, Nashville Veterans Administration Medical Center, Tennessee.
Reviews of Infectious Diseases
|March 1, 1990
Summary
Patients with renal insufficiency face unique antibiotic risks, including neurologic toxicity and coagulopathy. This review highlights these adverse reactions and offers management recommendations for safer antibiotic use.
Area of Science:
- Pharmacology
- Nephrology
- Clinical Toxicology
Background:
- Antibiotic-associated adverse reactions are a significant clinical concern.
- Patients with renal insufficiency represent a vulnerable population for these adverse effects.
- Many antibiotic adverse reactions are exacerbated or unique in the context of impaired renal function.