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Related Concept Videos

Renal Corpuscle01:20

Renal Corpuscle

The glomerulus and Bowman's capsule are two essential components of the nephron, which is the functional unit of the kidney. These microscopic structures play a critical role in the process of blood filtration to produce urine.
Glomerulus: Structure and Function
The glomerulus is a tiny, intricate network of capillaries located at the beginning of the nephron. It's enveloped by the Bowman's capsule and receives its blood supply from an afferent arteriole, which divides into numerous capillaries...

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Related Experiment Video

Updated: May 30, 2026

Renal Capsule Xenografting and Subcutaneous Pellet Implantation for the Evaluation of Prostate Carcinogenesis and Benign Prostatic Hyperplasia
08:38

Renal Capsule Xenografting and Subcutaneous Pellet Implantation for the Evaluation of Prostate Carcinogenesis and Benign Prostatic Hyperplasia

Published on: August 28, 2013

[Prostatic adenocarcinoma with glomeruloid structure].

Zhuo Liu1, Bao Chang, Shui-ming Guo

  • 1Department of Urology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology,Wuhan 430030, China.

Beijing Da Xue Xue Bao. Yi Xue Ban = Journal of Peking University. Health Sciences
|August 17, 2011
PubMed
Summary

Glomeruloid features are rare in prostatic adenocarcinoma but indicate malignancy. These structures are typically found in high-grade tumors, often with aggressive clinical behavior and spread.

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Area of Science:

  • Pathology
  • Urological Oncology

Context:

  • Prostatic adenocarcinoma is a common malignancy.
  • Glomeruloid features are unusual histological findings.

Purpose:

  • To determine the prevalence of glomeruloid features in prostatic adenocarcinoma.
  • To correlate these features with clinical data and patient outcomes.

Summary:

  • 196 prostatic adenocarcinoma specimens were analyzed for glomeruloid features.
  • Three cases (1.5%) exhibited glomeruloid structures, all with high Gleason scores (7-8).
  • These cases showed aggressive features like extraprostatic extension and metastasis, with poor prognoses.

Impact:

  • Glomeruloid structures are an uncommon but specific marker for malignancy in the prostate.
  • Their presence suggests a high-grade tumor with a propensity for aggressive behavior and spread.