Related Experiment Video

Updated: May 30, 2026

Assays for the Specific Growth Rate and Cell-binding Ability of Rotavirus
10:49

Assays for the Specific Growth Rate and Cell-binding Ability of Rotavirus

Published on: January 28, 2019

Characteristics of rotavirus gastroenteritis in hospitalized children in Israel

Sivan Perl1, Michael Goldman, Matitiahu Berkovitch

  • 1Pediatric Emergency Unit, Assaf Harofeh Medical Center, Zerifin, Israel.

The Israel Medical Association Journal : IMAJ
|August 18, 2011
PubMed

Insights

Rotavirus gastroenteritis in children presents with more vomiting and dehydration than other causes. This highlights the significant impact of rotavirus on pediatric hospitalizations and the need for effective interventions.

Area of Science:

  • Pediatric Infectious Diseases
  • Gastroenterology
  • Public Health

Background:

  • Diarrhea remains a primary cause of mortality in children globally.
  • Rotavirus is a significant pathogen responsible for severe childhood diarrhea and dehydration.

Purpose of the Study:

  • To compare demographic, clinical, and laboratory features of rotavirus gastroenteritis with other causes.
  • To identify key indicators differentiating rotavirus from non-rotavirus gastroenteritis in hospitalized children.

Main Methods:

  • Retrospective analysis of medical records for children (0-18 years) hospitalized with acute gastroenteritis.
  • Comparison of patients with confirmed rotavirus gastroenteritis against a rotavirus-negative cohort.

Main Results:

  • Rotavirus-positive patients showed significantly higher rates of vomiting (92% vs. 64%), lethargy (33% vs. 15%), and dehydration (40% vs. 24%).
  • Increased need for intravenous rehydration and longer hospital stays were observed in children with rotavirus gastroenteritis.

Conclusions:

  • Vomiting and dehydration are more prevalent in children hospitalized with rotavirus gastroenteritis compared to other etiologies.
  • These findings underscore the severity of rotavirus infections and inform clinical management strategies.
Abstract

More Related Videos

Assessment of Intestinal Transcytosis of Neonatal Escherichia coli Bacteremia Isolates08:32

Assessment of Intestinal Transcytosis of Neonatal Escherichia coli Bacteremia Isolates

Published on: February 17, 2023

Guided Protocol for Fecal Microbial Characterization by 16S rRNA-Amplicon Sequencing08:05

Guided Protocol for Fecal Microbial Characterization by 16S rRNA-Amplicon Sequencing

Published on: March 19, 2018

Related Concept Videos

Bacterial Gastroenteritis01:18

Bacterial Gastroenteritis

Bacterial gastroenteritis, characterized by diarrhea, abdominal cramps, and vomiting, is often caused by ingestion of contaminated food or water and is frequently associated with pathogenic Escherichia coli strains. These microbes exploit two principal mechanisms to inflict disease.Shiga toxin–producing E. coli, also referred to as STEC—notably O157:H7—release Shiga toxins that target ribosomes, blocking protein synthesis. The B subunit of the toxin binds the host glycolipid receptor...
Respiratory Syncytial Virus Disease01:29

Respiratory Syncytial Virus Disease

Human respiratory syncytial virus (RSV) is a widespread pathogen that primarily targets infants and young children but also poses a serious health risk to elderly and immunocompromised individuals. Belonging to the Pneumoviridae family, RSV is a negative-sense, single-stranded RNA virus within the Pneumovirus genus. Its global health burden is significant, with millions of cases annually resulting in hospitalizations and mortality, particularly in resource-limited settings. Although most...
Cholera01:25

Cholera

Cholera is an acute gastrointestinal disease caused by the Gram-negative bacterium Vibrio cholerae. It is transmitted primarily via the fecal-oral route through the ingestion of contaminated water or food.Vibrio cholerae is a motile, Gram-negative bacterium of the family Vibrionaceae, primarily associated with waterborne outbreaks in areas with inadequate sanitation. Although over 200 serogroups of V. cholerae exist, only O1 and O139 are responsible for epidemic cholera. The O1 serogroup,...
Poliomyelitis01:17

Poliomyelitis

Poliomyelitis is caused by poliovirus, a small, non-enveloped, positive-sense RNA virus of the Picornaviridae family and Enterovirus genus. Transmission occurs primarily via the fecal-oral route, often through ingestion of contaminated water or food. The virus initially replicates in the oropharynx and intestinal mucosa, particularly in lymphoid tissues such as the tonsils, Peyer’s patches, and regional lymph nodes. Primary viremia follows, allowing dissemination throughout the body.In most...
Reservoir of Infection01:30

Reservoir of Infection

Infectious diseases arise from intricate interactions between pathogens and their reservoirs. A reservoir of infection refers to the natural habitat where a pathogen lives, grows, and multiplies, serving as a continual source of infection. Reservoirs are broadly classified as either living or nonliving, and each plays a unique role in disease transmission, significantly influencing public health interventions and control strategies.Humans act as reservoirs for a wide array of pathogens,...
Drugs Affecting GI Tract Motility: Antimicrobials as Antidiarrheal Agents01:18

Drugs Affecting GI Tract Motility: Antimicrobials as Antidiarrheal Agents

Acute diarrhea, a common gastrointestinal disturbance, is characterized by the rapid evacuation of fluid stools, leading to an excessive weight in fluid. This condition typically arises from disorders affecting intestinal water and electrolyte transport. It can be triggered by an increased osmotic load within the intestine, excessive secretion of electrolytes and water, mucosal exudation of protein and fluid, or altered intestinal motility. The primary risks of acute diarrhea are dehydration...