Related Experiment Video
Updated: May 30, 2026
Analysis of Cerebral Vasospasm in a Murine Model of Subarachnoid Hemorrhage with High Frequency Transcranial Duplex Ultrasound
Published on: June 3, 2021
[Influence of hyperhomocysteinemic on the wavelet-analysis of cerebral blood flow]
Insights
This study investigated how vessel tone blockers affect cerebral blood flow in rats. Acute hyperhomocysteinemia increased flow oscillations, suggesting modulation factors maintain constant cerebral blood flow during autoregulation.
Area of Science:
- Neuroscience
- Physiology
- Biomedical Engineering
Abstract:
The objective of this study is to assess the effect of different blockers of a vessel tone on the cerebral blood flowmotion in rats using spectral analysis based on wavelets transform of the periodic oscillations of the cerebral laser Doppler flowmetry signal. Three frequency intervals were identified (0.01-0.04 Hz, 0.04-0.126 Hz, 0.126-0.4 Hz) corresponding to endothelial, neurogenic and myogenic origins. It was increase of amplitude in endothelial interval during acute hyperhomocysteinemie. We suppose that modulation factors form the value of cerebral flow which supports on constant level during autoregulation.
