Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Synthetic Biology

Synthetic Biology

Synthetic biology is an interdisciplinary science that involves using principles from disciplines such as engineering, molecular biology, cell biology, and systems biology. It involves remodeling existing organisms from nature or constructing completely new synthetic organisms for applications such as protein or enzyme production, bioremediation, value-added macromolecule production, and the addition of desirable traits to crops, to name a few.
Golden rice
Golden rice is a genetically modified...

Combinatorial Gene Control

Combinatorial Gene Control

Combinatorial gene control is the synergistic action of several transcriptional factors to regulate the expression of a single gene. The absence of one or more of these factors may lead to a significant difference in the level of gene expression or repression.
The expression of more than 30,000 genes is controlled by approximately 2000-3000 transcription factors. This is possible because a single transcription factor can recognize more than one regulatory sequence. The specificity in gene...

What is Genetic Engineering?

What is Genetic Engineering?

Gene Therapy

Gene Therapy

Gene therapy is a technique where a gene is inserted into a person’s cells to prevent or treat a serious disease. The added gene may be a healthy version of the gene that is mutated in the patient, or it could be a different gene that inactivates or compensates for the patient’s disease-causing gene. For example, in patients with severe combined immunodeficiency (SCID) due to a mutation in the gene for the enzyme adenosine deaminase, a functioning version of the gene can be inserted. The...

Gene Therapy

Gene Therapy

Gene therapy is a technique where a gene is inserted into a person’s cells to prevent or treat a serious disease. The added gene may be a healthy version of the gene that is mutated in the patient, or it could be a different gene that inactivates or compensates for the patient’s disease-causing gene. For example, in patients with severe combined immunodeficiency (SCID) due to a mutation in the gene for the enzyme adenosine deaminase, a functioning version of the gene can be inserted. The...

Genetic Lingo

Genetic Lingo

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

The Detection of Novel Nitazene-Class Opioids in Unregulated Drug Markets in Canada.

Drug and alcohol review·2026

Same author

Global emergence and γ-aminobutyric acid type A (GABA<sub>A</sub>) receptor activity of the new designer benzodiazepine ethylbromazolam.

Archives of toxicology·2026

Same author

The Bone Metastases and Exercise (BME) Hub: a MASCC-endorsed knowledge mobilization initiative to advance exercise recommendations for people with bone metastases.

Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer·2025

Same author

Applications of Plant-Made Fibroblast Growth Factor for Human Pluripotent Stem Cells.

Stem cells and development·2023

Same author

Considerations for Purchasing Drug Checking Technologies: Perspectives from Toronto's Drug Checking Service.

International journal of environmental research and public health·2023

Same author

Poly(3-hydroxybutyrate) Degradation by <i>Bacillus infantis</i> sp. Isolated from Soil and Identification of <i>phaZ</i> and <i>bdhA</i> Expressing PHB Depolymerase.

Journal of microbiology and biotechnology·2023

Search research articles

Related Experiment Video

Updated: May 30, 2026

Rapid Assembly of Multi-Gene Constructs using Modular Golden Gate Cloning

Rapid Assembly of Multi-Gene Constructs using Modular Golden Gate Cloning

Published on: February 5, 2021

Visual gene developer: a fully programmable bioinformatics software for synthetic gene optimization.

Sang-Kyu Jung¹, Karen McDonald

¹Department of Chemical Engineering and Materials Science, University of California, Davis, 1 Shields Ave, Davis, CA 95616, USA.

BMC Bioinformatics

|August 18, 2011

Summary

Visual Gene Developer is a free software tool that simplifies gene sequence analysis and optimization. It offers advanced features for researchers and bioinformaticians, enhancing gene synthesis applications.

More Related Videos

Automated Robotic Liquid Handling Assembly of Modular DNA Devices

Automated Robotic Liquid Handling Assembly of Modular DNA Devices

Published on: December 1, 2017

Inherent Dynamics Visualizer, an Interactive Application for Evaluating and Visualizing Outputs from a Gene Regulatory Network Inference Pipeline

Inherent Dynamics Visualizer, an Interactive Application for Evaluating and Visualizing Outputs from a Gene Regulatory Network Inference Pipeline

Published on: December 7, 2021

Related Experiment Videos

Last Updated: May 30, 2026

Rapid Assembly of Multi-Gene Constructs using Modular Golden Gate Cloning

Rapid Assembly of Multi-Gene Constructs using Modular Golden Gate Cloning

Published on: February 5, 2021

Automated Robotic Liquid Handling Assembly of Modular DNA Devices

Automated Robotic Liquid Handling Assembly of Modular DNA Devices

Published on: December 1, 2017

Inherent Dynamics Visualizer, an Interactive Application for Evaluating and Visualizing Outputs from a Gene Regulatory Network Inference Pipeline

Inherent Dynamics Visualizer, an Interactive Application for Evaluating and Visualizing Outputs from a Gene Regulatory Network Inference Pipeline

Published on: December 7, 2021

Area of Science:

Bioinformatics
Molecular Biology
Computational Biology

Background:

Decreasing costs of gene synthesis are increasing its popularity.
Gene synthesis offers advantages over natural genes for sequence optimization.
There is a need for user-friendly software to facilitate gene optimization.

Purpose of the Study:

To develop a stand-alone software for gene analysis and optimization.
To provide researchers with a tool for efficient gene sequence manipulation.

Main Methods:

Developed Visual Gene Developer software.
Integrated general gene analysis and optimization functions.
Included advanced features like mRNA secondary structure prediction and artificial neural network modeling.
Supported user-defined algorithms and programming modules using VBScript and JScript.

Main Results:

Visual Gene Developer offers an interactive interface for gene analysis and optimization.
Unique features include programming capability, ANN modeling, and multi-threaded computing.
The software supports the development of custom algorithms and modules.
Expandable functionality through script languages enhances its utility.

Conclusions:

Visual Gene Developer is a valuable tool for researchers performing gene analysis and optimization.
It also serves as a platform for bioinformaticians developing new algorithms.
The software is freely available for download.