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Control of Eating Behavior Using a Novel Feedback System
04:48

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Published on: May 8, 2018

Programming towards childhood obesity.

Patrick Tounian1

  • 1Department of Pediatric Nutrition, Armand Trousseau Hospital, Paris, France. p.tounian@trs.aphp.fr

Annals of Nutrition & Metabolism
|August 18, 2011
PubMed
Summary
This summary is machine-generated.

Childhood obesity is often programmed by genetic factors and prenatal influences, not just lifestyle. Understanding this "programming towards obesity" is key for targeted prevention and treatment strategies.

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Area of Science:

  • Pediatric Endocrinology
  • Genetics
  • Developmental Biology

Background:

  • Childhood obesity is increasingly prevalent, influenced by both genetic predisposition and environmental factors.
  • A constitutional susceptibility to fat gain, termed
  • programming towards obesity
  • is recognized as a necessary component for developing obesity in obesogenic environments.

Purpose of the Study:

  • To review the evidence for genetic and environmental factors contributing to childhood obesity programming.
  • To discuss the implications of obesity as a programmed disease for clinical management and prevention.

Main Methods:

  • Literature review of studies on genetic and environmental influences on childhood obesity.
  • Analysis of evidence for fetal and early postnatal programming of obesity.
  • Discussion of current treatment and prevention strategies in light of obesity programming.

Main Results:

  • Genetics plays a dominant role, with monogenic and polygenic forms of obesity identified.
  • Prenatal factors like maternal nutrition, diabetes, and smoking are implicated in programming obesity.
  • The role of early postnatal factors requires further investigation, with evidence being more questionable.

Conclusions:

  • Childhood obesity should be viewed as a programmed disease, necessitating a shift in clinical management and parental perception.
  • Prevention efforts should target at-risk children rather than the general pediatric population.
  • Further research into obesity programming is crucial for developing effective therapeutic and preventive approaches.