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Fluidity and lipid composition of mouse biomembranes during adaptation to ethanol
Alcoholism, Clinical and Experimental Research
|January 1, 1979
Abstract:
Showing that ethanol added in vitro increased the fluidity of mouse erythrocyte and synaptosomal membranes and that the same membranes isolated from mice after chronic treatment with ethanol had increased cholesterol and were resistant to ethanol in vitro, the study suggests that the animals had adapted to the chronic presence of the drug by changing their membrane lipid composition to offset the fluidizing effects of ethanol.