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Updated: May 30, 2026

A Microfluidic-based Hydrodynamic Trap for Single Particles
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A Microfluidic-based Hydrodynamic Trap for Single Particles

Published on: January 21, 2011

Individual particle handling in a microfluidic system based on parallel laser trapping.

Philippe Hamel1, Bastien Rachet, Michael Werner

  • 1Applied Optics Laboratory, School of Engineering, EPFL, Station 17, CH-1015 Lausanne, Switzerland. philippe.hamel@epfl.ch

Optics Letters
|August 18, 2011
PubMed
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This study introduces a novel optical trapping system with 64 laser traps for high-throughput particle analysis. The system enables rapid, parallel sorting and spectral analysis of biological particles in microfluidic devices.

Area of Science:

  • Biophotonics
  • Microfluidics
  • Analytical Chemistry

Background:

  • Optical trapping is crucial for manipulating microscopic particles.
  • Existing systems often lack the throughput for high-volume bioanalysis.
  • Integrating spectroscopy with trapping can enhance particle characterization.

Purpose of the Study:

  • To develop a highly parallel optical trapping system.
  • To integrate fluorescence spectroscopy for particle analysis.
  • To create an advanced bioanalytical platform for high-throughput applications.

Main Methods:

  • Utilizing an in-line array of 64 individually addressable near-infrared laser diodes.
  • Implementing a microfluidic chip to house the laser traps.
  • Incorporating an excitation/detection line for spectrally resolved fluorescence imaging.

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Last Updated: May 30, 2026

A Microfluidic-based Hydrodynamic Trap for Single Particles
10:13

A Microfluidic-based Hydrodynamic Trap for Single Particles

Published on: January 21, 2011

Use of Dual Optical Tweezers and Microfluidics for Single-Molecule Studies
06:53

Use of Dual Optical Tweezers and Microfluidics for Single-Molecule Studies

Published on: November 18, 2022

Plasmonic Trapping and Release of Nanoparticles in a Monitoring Environment
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Plasmonic Trapping and Release of Nanoparticles in a Monitoring Environment

Published on: April 4, 2017

Main Results:

  • Achieved highly parallel trapping in continuous flow (mm/s).
  • Demonstrated fast particle handling rates (particles/s).
  • Enabled spectral recording of trapped biological particles.

Conclusions:

  • The developed system offers a performing bioanalytical platform.
  • The system facilitates highly parallel analysis and sorting of particles.
  • This technology advances capabilities in microfluidic-based bioanalysis.