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Pancreatic injury in 284 patients with severe abdominal trauma: outcome, course, and treatment algorithm
Matthias Heuer1, Björn Hussmann, Rolf Lefering
1Department of General, Visceral and Transplantation Surgery, University Hospital of Essen, Hufelandstrasse 55, 45122 Essen, NRW, Germany.
Insights
Pancreatic trauma is present in 3.1% of severely injured patients with abdominal injuries. Higher grades of pancreatic injury (IV and V) significantly increase mortality and the need for surgical intervention.
Area of Science:
- Trauma Surgery
- Surgical Outcomes
- Abdominal Trauma
Background:
- Pancreatic trauma is a severe injury with significant morbidity and mortality.
- The prevalence and outcomes of pancreatic trauma in severely injured patients require further investigation.
Purpose of the Study:
- To assess the prevalence of pancreatic trauma in severely injured patients.
- To analyze the outcomes of pancreatic trauma in relation to injury severity.
- To evaluate the established treatment algorithm for pancreatic trauma.
Main Methods:
- Retrospective analysis of 51,425 patients from the Trauma Register of the German Society of Trauma Surgery (TR DGU) (1993-2009).
- Inclusion criteria: Injury Severity Score (ISS) ≥16, direct trauma center admission, ≥3 days treatment, age ≥16, and abdominal injury (Abbreviated Injury Scale [AIS](abdomen) ≥2).
- Comparison of patients with abdominal trauma versus those with additional pancreatic trauma (AIS(pancreas) 2-5).
Main Results:
- 18% of patients had documented abdominal injuries; 3.1% of these had associated pancreatic injuries.
- Pancreatic injury prevalence: AAST grades II (1.9%), III (0.6%), IV (0.3%), and V (0.2%).
- High-grade pancreatic injuries (AAST IV and V) correlated with significantly increased mortality (30.0% and 33.3%, respectively) and surgical intervention rates (80.6% and 81.8%, respectively).
Conclusions:
- This study provides the first comprehensive data on the prevalence and outcomes of pancreatic injury in a large cohort from the TR DGU.
- A treatment algorithm for pancreatic trauma has been developed based on current literature and study findings.
- Severe pancreatic trauma necessitates aggressive management due to high mortality and surgical intervention rates.
Purpose:
The relevance of pancreatic trauma in severely injured patients within a large collective has not been thoroughly analyzed yet. This study aimed at assessing the prevalence of pancreatic trauma in relation to the outcome and the currently established algorithm of treatment.
Methods:
Some 51,425 patients from the Trauma Register of the German Society of Trauma Surgery (TR DGU) (1993-2009) were retrospectively analyzed. All patients with an "injury severity score" ≥16, direct admission to a trauma center and subsequent treatment for at least 3 days, age ≥16, and an abdominal injury [abbreviated injury scale (AIS)(abdomen) ≥2] were included. Patients with abdominal trauma (AIS(abdomen) ≥2) were compared with patients with an additional pancreatic trauma (AIS(pancreas) 2-5).
Results:
Of 51,425 patients, 9,268 (18%) had documented abdominal injuries. Two hundred eighty-four (3.1%) patients with abdominal injury additionally showed a pancreatic injury (AIS(abdomen) ≥2, AIS(pancreas) 2-5) and were analyzed in dependency of the classification of the American Association for the Surgery of Trauma (AAST) organ severity score. AAST-pancreas: II°, 1.9%; III°, 0.6%; IV°, 0.3%; and V°, 0.2%. Patients with leading pancreatic injury (grades IV and V) thereby showed a significant increase of mortality (IV°, 30.0% and V°, 33.3%) and an increase of the need for surgical intervention (IV°, 80.6% and V°: 81.8%).
Conclusions:
The results presented here show the prevalence and the outcome of pancreas injury in a large collective within the TR DGU for the first time. Based on the current literature and the findings, a treatment algorithm has been developed.
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