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Published on: September 26, 2018
National differences in screening programmes for cardiovascular risks could obstruct understanding of cardiovascular
S L Thio1, Th B Twickler, M J Cramer
1Medical Faculty, Leiden University Medical Centre, Leiden, the Netherlands, sl_thio@hotmail.com.
Insights
Differences in national guidelines impact cardiovascular risk management. French guidelines achieve better LDL-cholesterol targets, while Dutch patients have lower levels and higher statin use.
Area of Science:
- Cardiology
- Public Health
- Health Services Research
Background:
- Cardiovascular disease remains a leading cause of mortality in North-West Europe.
- Despite European initiatives, cardiovascular risk factors are inconsistently diagnosed and treated.
Purpose of the Study:
- To compare national guidelines and patient profiles in French and Dutch cardiovascular clinics.
- To identify differences in cardiovascular risk assessment and treatment approaches.
Main Methods:
- Evaluation of first consultations in French and Dutch cardiovascular referral clinics.
- Analysis of national guidelines and patient demographics, focusing on LDL-cholesterol levels and statin use.
Main Results:
- Significant variations observed in cardiovascular risk assessment programs and LDL-cholesterol target levels between French and Dutch guidelines.
- French guidelines resulted in more patients achieving target LDL-cholesterol levels compared to Dutch guidelines.
- Dutch patients presented with lower LDL-cholesterol levels and higher statin utilization than French patients.
Conclusions:
- National differences in patient management strategies complicate direct comparisons of cardiovascular prevention programs.
- Extrapolation of results from cardiovascular prevention programs requires careful consideration of these national variations.
Introduction:
In North-West Europe, cardiovascular disease is still a major cause of death and despite several efforts (e.g. European guidelines and conferences) cardiovascular risk factors are still inconsistently diagnosed and treated.
Methods:
We evaluated the first consultations of patients in two cardiovascular referral clinics in France and the Netherlands, while evaluating the differences in national guidelines and between the profiles of patients at their first consultation.
Results:
Notable differences exist between the two locally used guidelines in their programmes of cardiovascular risk assessment and their definition of LDL-cholesterol target levels. With regard to the LDL-cholesterol levels, more patients are 'on target' when using the French guideline than when using the Dutch guideline. Evaluation of the patient's profile at first presentation showed that the LDL-cholesterol levels were significantly lower in the Dutch patients (n = 77) compared with the French patients (n = 119). Dutch patients used significantly more statins than French patients.
Conclusion:
Despite the small study population included in this study, we found that comparison of daily care (as part of a primary prevention programme) is rather difficult due to several national differences in the approach to patients. All these factors combined should be taken into account, when discussing and extrapolating results obtained from analysis of cardiovascular prevention programmes.
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