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Related Experiment Video

Updated: May 30, 2026

Full-Circle Cauterization of Limbal Vascular Plexus for Surgically Induced Glaucoma in Rodents

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[Relative afferent pupillary defect in glaucoma].

Karolina Skorkovská¹, H Wilhelm, H Lüdtke

¹Augenklinik, Universitätsklinikum Tübingen. skorka@centrum.cz

Klinische Monatsblatter Fur Augenheilkunde

|August 18, 2011

Summary

This summary is machine-generated.

Relative afferent pupillary defect (RAPD) is present in about one-third of primary open-angle glaucoma patients, particularly those with advanced visual field loss and asymmetry. The swinging-flashlight test is recommended for glaucoma diagnosis.

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Area of Science:

Ophthalmology
Neuroscience

Context:

Glaucoma diagnosis relies on visual field testing and optic nerve assessment.
Relative afferent pupillary defect (RAPD) is a potential indicator of optic nerve dysfunction in glaucoma.
The relationship between RAPD and glaucoma severity/asymmetry requires further elucidation.

Purpose:

To determine the frequency of RAPD in primary open-angle glaucoma (POAG).
To investigate the correlation between RAPD and the severity of visual field defects.
To assess the association between RAPD and visual field asymmetry in POAG patients.

Summary:

A retrospective study included 100 POAG patients; 34% exhibited RAPD.
Visual field analysis of 85 patients revealed significantly more advanced visual field loss (p < 0.01) and greater inter-eye asymmetry (p < 0.01) in those with RAPD.
Visual field asymmetry demonstrated good predictive value for RAPD (AUC = 0.81).

Impact:

RAPD is a common finding in approximately one-third of POAG cases.
The presence of RAPD correlates with more severe and asymmetric visual field defects.
Routine inclusion of the swinging-flashlight test in glaucoma diagnostics is advised to aid in identifying patients with significant visual field impairment.