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Ultrasound-guided Botulinum Toxin-A Injections: A Method of Treating Sialorrhea

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Published on: November 9, 2016

A split-face study using botulinum toxin type B to decrease facial erythema index.

Yu-Jin Oh¹, Na-Young Lee, Dong-Hye Suh

¹Department of Dermatology, College of Medicine, Kyung Hee University, Seoul, Republic of Korea.

Journal of Cosmetic and Laser Therapy : Official Publication of the European Society for Laser Dermatology

|August 19, 2011

Summary

This summary is machine-generated.

Botulinum toxin type B (BTX-B) showed no significant improvement for facial flushing in a split-face trial. This study is the first to investigate BTX-B for this common skin concern.

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Area of Science:

Dermatology
Aesthetic Medicine

Background:

Facial flushing presents as a common cosmetic concern.
The efficacy of botulinum toxin type B (BTX-B) for facial flushing has not been previously studied.

Purpose of the Study:

To evaluate the effectiveness of BTX-B in improving facial flushing.

Main Methods:

A randomized, split-face trial involving 15 Korean subjects with facial flushing.
BTX-B was injected on one side of the face, with the contralateral side receiving saline as a control.
Skin tone changes were assessed via self-assessment and mexameter measurements.

Main Results:

Mexameter readings indicated significant erythema improvement on both sides at 8 weeks.
No significant difference in objective erythema reduction was observed between BTX-B and saline sides.
Subjective patient satisfaction levels were comparable between the treated and control sides.

Conclusions:

BTX-B was found to be ineffective for treating facial flushing.
This study represents the first investigator-initiated, randomized, split-face trial assessing BTX-B for facial flushing.