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Updated: May 30, 2026

3D-Neuronavigation In Vivo Through a Patient's Brain During a Spontaneous Migraine Headache
Published on: June 2, 2014
Transient global amnesia triggered by migraine in monozygotic twins
Ferdinando Maggioni1, Federico Mainardi, Matteo Bellamio
1Department of Neurosciences, Headache Centre, University of Padua, Padova, Italy. ferdinando.maggioni@unipd.it
Abstract:
Transitory global amnesia and migraine without aura are diseases with unclear pathophysiologic mechanisms, but with evidence of comorbidity. We describe twin monozygotic brothers, both presenting episodes of transitory global amnesia occurring only during attacks of migraine without aura. This report supports the hypothesis of a common underlying pathogenetic mechanism, possibly related to the cortical spreading depression. Furthermore, a common genetic trait in both the diseases or more probably in a particular subgroup of patients could be hypothesized.
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