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Related Concept Videos

Blood Transfusion01:15

Blood Transfusion

Blood transfusion is a critical medical procedure that saves lives and treats various medical conditions. It involves transferring blood from a donor to a recipient. This process requires a thorough understanding of the ABO blood group system and its associated antigens and antibodies.
Blood Transfusion Overview
A blood transfusion is a medical procedure used to replace blood lost due to injury, surgery, or to treat conditions such as anemia or cancer. During a transfusion, donor blood is...
Blood Transfusion and Agglutination02:45

Blood Transfusion and Agglutination

Blood transfusion is a therapeutic measure to restore the blood volume after extensive blood loss due to an accident or a medical procedure. Blood transfusion involves drawing a certain amount of blood from a suitable donor and infusing it into the recipient.
History
The history of blood transfusion dates back to the 17th century, when early attempts were made in animals. In 1818 James Blundell, a British doctor, performed the first successful human blood transfusion. Later in 1900, Karl...

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Related Experiment Video

Updated: May 30, 2026

A Semi-automated Approach to Preparing Antibody Cocktails for Immunophenotypic Analysis of Human Peripheral Blood
08:17

A Semi-automated Approach to Preparing Antibody Cocktails for Immunophenotypic Analysis of Human Peripheral Blood

Published on: February 8, 2016

[Reference values of clinical donor blood analysis].

M S Tropskaia, S A Lugovskaia, E M Danilova

    Klinicheskaia Laboratornaia Diagnostika
    |August 20, 2011
    PubMed
    Summary

    New reference ranges for blood donors suggest extending normal values for platelets, red blood cells, hemoglobin, and packed cell volume. These updated hemogram parameters are crucial for blood donation eligibility assessments.

    Area of Science:

    • Hematology
    • Clinical Pathology
    • Blood Transfusion Science

    Context:

    • Analysis of basic hemogram parameters in a cohort of 835 blood donors.
    • Utilized an ADVIA 120 hematology analyzer for precise measurements.
    • Included a balanced cohort of 421 men and 414 women aged 18 to 67 years.

    Purpose:

    • To establish updated reference ranges for key hemogram parameters in blood donors.
    • To compare newly calculated ranges with previously established unified normal values.
    • To inform blood donation eligibility criteria based on current donor population data.

    Summary:

    • Calculated reference ranges based on data distribution (mean +/- 2alpha or 2.5-97.5 percentiles).
    • Findings indicate a need to broaden normal ranges for platelets, red blood cells, hemoglobin, and packed cell volume.

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    Dried Blood Spots - Preparing and Processing for Use in Immunoassays and in Molecular Techniques
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    Dried Blood Spots - Preparing and Processing for Use in Immunoassays and in Molecular Techniques

    Published on: March 13, 2015

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    Last Updated: May 30, 2026

    A Semi-automated Approach to Preparing Antibody Cocktails for Immunophenotypic Analysis of Human Peripheral Blood
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    Published on: February 8, 2016

    Detection of Residual Donor Erythroid Progenitor Cells after Hematopoietic Stem Cell Transplantation for Patients with Hemoglobinopathies
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    11:28

    Dried Blood Spots - Preparing and Processing for Use in Immunoassays and in Molecular Techniques

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  • The study highlights discrepancies with older, unified normal values.
  • Impact:

    • Recommends adjusting normal hemogram ranges for blood donation screening.
    • Emphasizes the importance of updated parameters for accurate donor selection.
    • Aims to improve the safety and efficiency of blood donation processes through evidence-based criteria.