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Updated: May 30, 2026

Isolation and Culture of Primary Endothelial Cells from Canine Arteries and Veins
Published on: November 18, 2016
Lingual haemangiosarcoma in a crossbred dog
Laura J Owen1, James M Grierson, Janet C Patterson-Kane
1Small Animal Hospital, Department of Clinical Veterinary Science, Langford House, Bristol, UK. laura.owen@bristol.ac.uk.
Abstract:
An eight-year-old, male neutered, crossbred dog was presented for investigation of a lingual mass of four months duration. Oral examination revealed a 7 cm × 5 cm soft, fluctuant mass at the caudal aspect of the tongue. Ultrasound examination of the mass demonstrated mixed echogenicity, with cavitations containing hypoechoic and anechoic regions. Lingual haemangiosarcoma was diagnosed on histopathological examination of multiple biopsy samples, with confirmation of the vascular endothelial origin of tumour cells by positive immunolabelling for factor VIII-related antigen.

