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Studying Cryptosporidium Infection in 3D Tissue-derived Human Organoid Culture Systems by Microinjection
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Studying Cryptosporidium Infection in 3D Tissue-derived Human Organoid Culture Systems by Microinjection

Published on: September 14, 2019

An Irish perspective on Cryptosporidium. Part 1.

Annetta Zintl1, Grace Mulcahy, Theo de Waal

  • 1UCD School of Agriculture, Food Science and Veterinary Medicine and Conway Institute of Biomedical and Biomolecular Research, University College Dublin, Ireland.

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Cryptosporidiosis is a major cause of diarrhea in young animals and a threat to public health in Ireland. Its spread in untreated water highlights the need for better surveillance and a dedicated reference facility.

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Studying Cryptosporidium Infection in 3D Tissue-derived Human Organoid Culture Systems by Microinjection
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A Modified EPA Method 1623 that Uses Tangential Flow Hollow-fiber Ultrafiltration and Heat Dissociation Steps to Detect Waterborne Cryptosporidium and Giardia spp.
12:11

A Modified EPA Method 1623 that Uses Tangential Flow Hollow-fiber Ultrafiltration and Heat Dissociation Steps to Detect Waterborne Cryptosporidium and Giardia spp.

Published on: July 9, 2012

Area of Science:

  • Veterinary Parasitology
  • Environmental Health
  • Public Health

Background:

  • Cryptosporidiosis, a protozoal disease, causes significant illness in humans and is a primary cause of diarrhea in neonatal ruminants.
  • The epidemiology of Cryptosporidium in Ireland is poorly understood despite its threat to both animal and public health.
  • Environmental studies indicate the waterborne parasite is prevalent in untreated Irish water bodies.

Purpose of the Study:

  • To review the current understanding of cryptosporidiosis in the Irish context.
  • To highlight the vulnerability of Ireland to large-scale outbreaks due to its hydrogeology and agricultural practices.
  • To emphasize the necessity of establishing a dedicated reference facility for active surveillance.

Main Methods:

  • Literature review of existing studies on Cryptosporidium in Ireland.
  • Analysis of environmental factors contributing to parasite prevalence.
  • Assessment of public and animal health implications.

Main Results:

  • Cryptosporidium is widespread in untreated water sources across Ireland.
  • Ireland's hydrogeological conditions and high livestock density increase outbreak risk.
  • Current surveillance for this waterborne parasite is inadequate.

Conclusions:

  • Urgent need for a reference facility to conduct active surveillance of cryptosporidiosis in Ireland.
  • Improved water treatment and management strategies are essential.
  • Addressing cryptosporidiosis is critical for safeguarding animal and human health in Ireland.