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Related Concept Videos

The Blood-brain Barrier00:49

The Blood-brain Barrier

Overview
Brain Imaging01:14

Brain Imaging

Brain imaging technologies provide critical insights into both the structure and function of the human brain, enabling medical professionals and researchers to diagnose, study, and treat neurological disorders or psychiatric disorders more effectively.
These technologies include computerized axial tomography (CAT or CT scans), positron-emission tomography (PET scans),  magnetic resonance imaging (MRI),  functional magnetic resonance imaging (fMRI), and Transcranial Magnetic Stimulation (TMS).
Neuroplasticity01:01

Neuroplasticity

Neuroplasticity reflects the brain's remarkable capacity to adapt and evolve, responding dynamically to learning, experiences, or injury by reorganizing its neural circuitry. This reorganization involves creating new neural connections and refining old ones through a series of biological processes that contribute to the brain's lifelong development and adaptability.
Cerebrospinal Fluid01:21

Cerebrospinal Fluid

Cerebrospinal fluid (CSF) is a colorless liquid that flows around the brain and the spinal cord, playing a vital role in the protection, support, and overall function of the central nervous system (CNS). CSF production, circulation, and absorption are tightly regulated processes essential for the brain and spinal cord to function properly.
CSF Production
CSF is produced mainly in the choroid plexus, a network of capillaries and ependymal cells located within the ventricular system of the brain.
Organization of the Brain01:30

Organization of the Brain

The brain is an integral component of the nervous system and serves as the center for processing sensory inputs, making decisions, and directing bodily actions. This complex organ is organized into three primary sections: the hindbrain, midbrain, and forebrain, each responsible for a range of vital functions.
Hindbrain
The hindbrain, located at the base of the brain, plays a vital role in regulating automatic processes that sustain life. It includes the medulla oblongata, which is essential for...
Traumatic Brain Injury l: Introduction01:28

Traumatic Brain Injury l: Introduction

DefinitionTraumatic brain injury, or TBI, is a disturbance of normal brain function induced by an external mechanical force, such as a direct blow to the head or a penetrating injury. It can affect both brain structure and function, producing a wide range of clinical outcomes. TBI is a heterogeneous condition, meaning its effects may differ based on the type, location, and severity of the injury.Basis of ClassificationTBI is classified based on severity, injury mechanism, or pathophysiology. In...

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Related Experiment Video

Updated: May 30, 2026

Translational Brain Mapping at the University of Rochester Medical Center: Preserving the Mind Through Personalized Brain Mapping
13:12

Translational Brain Mapping at the University of Rochester Medical Center: Preserving the Mind Through Personalized Brain Mapping

Published on: August 12, 2019

Protecting brains, not simply stimulating minds.

Jack P Shonkoff1

  • 1Center on the Developing Child at Harvard University, 50 Church Street, Cambridge, MA 02138, USA. jack_shonkoff@harvard.edu

Science (New York, N.Y.)
|August 20, 2011
PubMed
Summary

Early childhood education needs both learning science and adversity biology interventions. Combining cognitive enrichment with stress mitigation supports healthy brain development for better outcomes.

Area of Science:

  • Early childhood education
  • Neuroscience
  • Developmental psychology

Background:

  • Early learning environments impact neurodevelopment.
  • Stressful experiences can disrupt crucial skill development.

Purpose of the Study:

  • Integrate cognitive-linguistic enrichment with interventions addressing early adversity.
  • Enhance the developmental trajectory of executive functions, emotional regulation, and behavioral adaptation.

Main Methods:

  • Leveraging neuroplasticity during sensitive developmental periods.
  • Combining educational enrichment with protective biological interventions.

Main Results:

  • Neuroplasticity supports skill development when stress is mitigated.

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A Human Blood-Brain Interface Model to Study Barrier Crossings by Pathogens or Medicines and Their Interactions with the Brain
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  • Interventions can foster positive adaptation despite early adversity.
  • Conclusions:

    • A dual approach is necessary for optimal early childhood development.
    • Collaboration among scientists, practitioners, and policymakers is crucial for effective strategies.