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Related Experiment Video

Updated: May 30, 2026

A Microfluidic Chip for the Versatile Chemical Analysis of Single Cells
15:41

A Microfluidic Chip for the Versatile Chemical Analysis of Single Cells

Published on: October 15, 2013

High-content screening in microfluidic devices.

Raymond Cheong1, Saurabh Paliwal, Andre Levchenko

  • 1Johns Hopkins University, Department of Biomedical Engineering, 3400 N. Charles St., Baltimore, MD 21218, USA.

Expert Opinion on Drug Discovery
|August 20, 2011
PubMed
Summary
This summary is machine-generated.

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Microfluidic technology enables miniaturized high-content screening (HCS), offering cost savings and large-scale primary cell analysis. This advancement promises broader application of HCS in drug discovery.

Area of Science:

  • Biotechnology
  • Drug Discovery
  • Microfluidics

Background:

  • Miniaturization is crucial for advancing high-content screening (HCS).
  • Microfluidic technology offers unprecedented miniaturization potential for HCS.
  • This enables reduced reagent costs and large-scale primary cell screening.

Purpose of the Study:

  • To highlight a microfluidic platform for HCS.
  • To discuss the advantages of miniaturized HCS.

Main Methods:

  • Implementation of HCS assays in a microfluidic format.
  • Perspective on a real-world example from the authors' work.

Main Results:

  • Microfluidics enables cost savings and high-throughput screening on primary cells.

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Last Updated: May 30, 2026

A Microfluidic Chip for the Versatile Chemical Analysis of Single Cells
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Published on: October 15, 2013

Generation of Dynamical Environmental Conditions using a High-Throughput Microfluidic Device
14:48

Generation of Dynamical Environmental Conditions using a High-Throughput Microfluidic Device

Published on: April 17, 2021

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  • Improved accuracy and ability to study complex stimuli are key benefits.
  • Ease of automation, integration, and scaling are demonstrated.

    • Conclusions:

    • Microfluidics-based HCS platforms offer significant advantages over conventional methods.
    • This technology will drive advancements and broader applicability of HCS in drug discovery.