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Related Concept Videos

Microbiome of the Eye01:22

Microbiome of the Eye

The human eye has a specialized microbiota that reflects its unique anatomical and immunological environment. This low-biomass microbial community predominantly colonizes the conjunctiva and eyelid margins, playing a vital role in ocular surface homeostasis and defense. Despite its proximity to the richly colonized facial skin, the ocular surface maintains a distinct microbial profile due to continuous mechanical and biochemical defense mechanisms.The conjunctival surface hosts fewer microbial...

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Updated: May 30, 2026

Iris Fixation via External Pentagram Suturing
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Published on: May 5, 2022

[Paecilomyces lilacinus keratitis].

A-K B Maier1, A Reichenbach, P Rieck

  • 1Klinik für Augenheilkunde, Charité - Universitätsmedizin Berlin, Campus Virchow-Klinikum, Augustenburger Platz 1, 13353 Berlin. anna-karina.maier@charite.de

Der Ophthalmologe : Zeitschrift Der Deutschen Ophthalmologischen Gesellschaft
|August 20, 2011
PubMed
Summary
This summary is machine-generated.

Paecilomyces lilacinus rarely causes contact lens-associated keratitis. This fungal infection is challenging to treat due to antifungal resistance, often leading to poor visual outcomes.

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Area of Science:

  • Ophthalmology
  • Mycology
  • Infectious Diseases

Background:

  • Contact lens-associated keratitis (CLAK) poses a significant risk to ocular health.
  • Fungal keratitis, particularly from rare organisms like Paecilomyces lilacinus, presents diagnostic and therapeutic challenges.

Observation:

  • A case of a female patient presenting with contact lens-associated keratitis is detailed.
  • Paecilomyces lilacinus was identified as the causative agent in the corneal abrasion.

Findings:

  • The infection demonstrated resistance to multiple antifungal drugs, complicating treatment.
  • Despite voriconazole therapy, a keratoplasty à chaud (emergency corneal transplant) was required.

Implications:

  • This case highlights the potential for Paecilomyces lilacinus to cause severe keratitis.
  • Antifungal resistance in fungal keratitis necessitates exploring alternative treatment strategies and emphasizes prompt diagnosis for better outcomes.