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Thunderclap headache triggered by micturition: responsive to nimodipine
Yuan-Yuan Han1, Wei Gui, Jin Zhu
1Department of Neurology, The First Hospital of Anhui Medical University, Jixi Road 218, Hefei, 230022, China.
Primary thunderclap headache (TCH) is rare and usually triggered by exertion. This case highlights micturition as a potential trigger for primary TCH, responding to nimodipine treatment.
Area of Science:
- Neurology
- Headache Medicine
Background:
- Primary thunderclap headache (TCH) is a distinct neurological emergency characterized by abrupt, severe headache onset.
- Common triggers include physical exertion like coughing or sexual activity.
- Micturition is a known trigger for secondary TCH associated with pheochromocytoma, but not typically for primary TCH.
Observation:
- A patient presented with recurrent thunderclap headaches.
- Headaches consistently occurred immediately following micturition.
- This pattern suggested a link between urination and primary TCH in this individual.
Findings:
- The patient's primary TCH episodes were directly linked to micturition.
- Treatment with nimodipine at a therapeutic dosage successfully resolved the headaches.
- This suggests nimodipine may be effective in managing primary TCH triggered by micturition.
Implications:
- Micturition should be considered a potential trigger for primary TCH.
- This case expands the understanding of primary TCH triggers beyond physical exertion.
- Nimodipine may represent a novel therapeutic option for this specific TCH presentation.
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