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A Method for Generating Pulmonary Neutrophilia Using Aerosolized Lipopolysaccharide
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A Method for Generating Pulmonary Neutrophilia Using Aerosolized Lipopolysaccharide

Published on: December 15, 2014

[Effect of lipopolysaccharide and hypoxia on rat neutrophils in vitro]

Magdalena Salwińska1, Danuta Uracz, Wojciech Uracz

  • 1Katedra Farmakologii, Uniwersytet Jagielloński Collegium Medicum, Kraków. m.salwinska@interia.pl

Folia Medica Cracoviensia
|August 23, 2011
PubMed

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Lipopolysaccharides (LPS) are crucial components of the outer membrane of Gram-negative bacteria, serving both structural and functional roles. It contributes to membrane stability and protects bacteria from host immune responses. LPS is composed of three major regions—lipid A, a core oligosaccharide, and an O antigen. The biosynthesis and assembly of LPS involve a highly coordinated set of enzymatic reactions and transport mechanisms. Additionally, LPS is recognized as an endotoxin, triggering...