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Isolated compounds from Sorghum bicolor L. inhibit the classical pathway of the complement

Hyung-In Moon1, Young-Choon Lee, Jai-Heon Lee

  • 1Department of Medicinal Biotechnology, College of Natural Resources and Life Science, Dong-A University, Busan 604-714, South Korea.

Immunopharmacology and Immunotoxicology
|August 23, 2011
PubMed

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Complement System

The complement system is a group of approximately 20 plasma proteins that strengthen the body's defenses against infections through opsonization, inflammation, and cell lysis. Opsonization involves coating pathogens with complement proteins, making them more recognizable and facilitating phagocyte engulfment. Certain complement proteins induce inflammation that attracts immune cells to the site of infection. Cell lysis involves the destruction of pathogens through the formation of a membrane...