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Updated: May 30, 2026

Echocardiographic Evaluation of Atrial Communications before Transcatheter Closure
Published on: February 8, 2022
The fifth chamber of the heart: huge left atrial aneurysm
Hsiao-Feng Hu1, Tsun-Hou Chang, Chien-Sheng Chen
1Department of Emergency Medicine, Tri-Service General Hospital, National Defense Medical Center, Taipei, Taiwan.
Insights
A rare huge left atrial aneurysm, mimicking cardiomegaly, was diagnosed in a woman with palpitations. Early surgery is recommended for this cardiac anomaly to prevent complications.
Area of Science:
- Cardiology
- Radiology
- Cardiac Surgery
Background:
- Cardiomegaly is a common emergency department finding with diverse causes.
- Left atrial abnormalities can mimic cardiomegaly on chest radiography.
- Atrial tachyarrhythmia and thromboembolic events are potential complications of left atrial aneurysms.
Observation:
- A 37-year-old woman presented with palpitations and electrocardiogram findings of atrial fibrillation.
- Chest radiograph revealed cardiomegaly with prominent left heart border.
- Transthoracic echocardiography showed an echo-free chamber adjacent to the left ventricle.
Findings:
- Multidetector-row computed tomography confirmed a rare huge left atrial aneurysm.
- This cardiac anomaly is often asymptomatic until adulthood.
- Diagnosis was aided by multidetector-row computed tomography, a less common diagnostic tool for this condition.
Implications:
- Early surgical intervention is advised, even for asymptomatic patients.
- Prompt treatment can prevent myocardial dysfunction, atrial fibrillation, and systemic embolism.
- This case highlights the importance of considering rare cardiac anomalies in the differential diagnosis of cardiomegaly.
Abstract:
Cardiomegaly is a common but nonspecific finding in the emergency department. The etiology may be explained by left ventricular dilation, biventricular dilation, right ventricular dilation, or pericardial abnormalities, or it may be found to be spurious on the echocardiogram. Rarely, isolated abnormalities of the atrium, particularly the left atrium, may cause abnormalities on the chest radiograph but will not cause true cardiomegaly. We reported a 37-year-old woman who presented with persistent palpitation of a 6-hour duration. An electrocardiogram revealed atrial fibrillation with rapid ventricular response. A chest radiograph showed cardiomegaly with unusual prominence of the left heart border. A subsequent transthoracic echocardiography demonstrated an echo-free chamber adjacent to the left lateral wall of the left ventricle. The diagnosis of a rare huge left atrial aneurysm was finally established by multidetector-row computed tomography, which had been seldom used as a diagnostic tool in the past. Patients with this cardiac anomaly usually are asymptomatic until the second or third decade of life, when the aneurysms can reach remarkable sizes and are often complicated with atrial tachyarrhythmia or thromboembolic events. Early surgical intervention is advised even in asymptomatic patients to prevent the occurrence of myocardial dysfunction, atrial fibrillation, and systemic embolism.
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