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Related Concept Videos

Open Angle Glaucoma: Treatment01:27

Open Angle Glaucoma: Treatment

In open-angle glaucoma, the iridocorneal angle remains open, but the trabecular meshwork becomes stiff, slowing down the outflow of aqueous humor. This causes a buildup of aqueous humor in the anterior chamber, leading to a sudden increase in intraocular pressure. The treatment for open-angle glaucoma focuses on reducing the elevated intraocular pressure by either decreasing the secretion of aqueous humor or increasing its outflow.
Drugs such as carbonic anhydrase inhibitors, α2- and...
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Glaucoma is an eye condition characterized by increased intraocular pressure that damages the retina and optic nerve, leading to irreversible blindness if left untreated. The human eye has various components, including the cornea, iris, pupil, lens, and optic nerve. Aqueous humor is secreted by the epithelium of the ciliary body in the posterior chamber and flows through the trabecular meshwork and canal of Schlemm, maintaining normal intraocular pressure. The trabecular meshwork and the canal...
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Angle Closure Glaucoma: Treatment

Angle-closure glaucoma, or closed-angle glaucoma, is an eye condition where the iris bulges out and blocks the iridocorneal angle, resulting in a buildup of aqueous humor and increased intraocular pressure. Immediate medical attention is necessary due to the sudden onset of symptoms. The treatment for angle-closure glaucoma includes short-term and long-term approaches. Short-term treatment involves using eye drops like pilocarpine to lower intraocular pressure by increasing aqueous humor...
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Ophthalmic drug delivery faces major limitations due to poor absorption across the corneal membrane. This process is primarily driven by diffusion and is influenced by two main factors: the physicochemical properties of the drug and tear drainage. Most ophthalmic drugs, such as pilocarpine, epinephrine, atropine, and local anesthetics, are weak bases. They are typically formulated at an acidic pH to enhance chemical stability. However, this leads to high ionization, reducing their ability to...

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Assessing Early Stage Open-Angle Glaucoma in Patients by Isolated-Check Visual Evoked Potential
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The relationship between glaucoma medication adherence, eye drop technique, and visual field defect severity.

Betsy Sleath1, Susan Blalock, David Covert

  • 1Division of Pharmaceutical Outcomes and Policy, Eshelman School of Pharmacy, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27599-7590, USA. betsy_sleath@unc.edu

Ophthalmology
|August 23, 2011
PubMed
Summary

Patient adherence to glaucoma medication is linked to visual field defect severity. Improving medication adherence and self-efficacy is crucial for better glaucoma management and outcomes.

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Area of Science:

  • Ophthalmology
  • Public Health

Background:

  • Glaucoma is a progressive optic neuropathy often managed with eye drops.
  • Patient adherence to medication regimens is critical for effective glaucoma control.
  • Self-efficacy in medication use can influence adherence and treatment outcomes.

Purpose of the Study:

  • To investigate the association between patient adherence and eye drop technique with visual field defect severity in glaucoma patients.
  • To examine the relationship between general glaucoma adherence self-efficacy and eye drop technique self-efficacy with visual field defect severity.

Main Methods:

  • A cross-sectional study was conducted at a single private practice.
  • Patient adherence was measured using Medication Events Monitoring System (MEMS) devices.
  • Eye drop technique was assessed via video recording, and self-efficacy was measured using validated scales. Multivariate logistic regression was employed for data analysis.

Main Results:

  • Lower adherence (<80% via MEMS) was significantly associated with worse visual field defect severity.
  • Reduced general glaucoma medication adherence self-efficacy correlated significantly with worse defect severity.
  • Eye drop technique and eye drop technique self-efficacy did not show a significant relationship with visual field defect severity.

Conclusions:

  • Healthcare providers should assess patient adherence to glaucoma medications.
  • Interventions to improve adherence and self-efficacy are necessary for patients with poor medication adherence.
  • Targeted support can enhance patients' ability and confidence in managing glaucoma with eye drops.