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Takotsubo cardiomyopathy: reversible elevation in microcirculatory resistance
Jamie Layland1, Robert Whitbourn, Andrew Macisaac
1Department of Cardiology, St Vincent's Hospital, Melbourne, Victoria, Australia. jamielayland@hotmail.com
Abstract:
We present a case of takotsubo cardiomyopathy and demonstrate an initial elevation of microcirculatory resistance (IMR) that reduced on follow-up evaluation. This corresponded with improvements in left ventricular function. We postulate that the changes in microvascular resistance reflect favourable left ventricular microvascular remodelling. The measurement of IMR, a novel marker of microcirculatory dysfunction, provides novel insights into the pathophysiology of this condition.
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