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Percutaneous endoscopic gastrostomy and peristomal infection: an avoidable complication with the use of a minimum
Renato Borges Fagundes1, João Carlos Cantarelli, Kalil Fontana
1Gastroenterology Department of Hospital Universitário de Santa Maria, Universidade Federal de Santa Maria, Brazil. fagundesrb@gmail.com
Background:
Percutaneous endoscopic gastrostomy (PEG) is a fast and simple method. Although considered safe, PEG is associated with many potential complications. Peristomal infection is the complication most frequently reported.
Objective:
To analyze patients who underwent PEG and the association of peristomal infection with the extent of skin incision (SI) and usage of prophylactic antibiotics (PA).
Methods:
A retrospective review of the records of 120 patients who underwent PEG was carried out. Patients were divided into 3 subgroups: (1) Patients with SI 10 mm/without PA, (2) Patients with SI up to 5 mm/without PA, and (3) Patients with SI up to 5 mm/with PA.
Results:
Peristomal infection occurred in 12.8% of patients from subgroup 1, and in 2.2% of patients from subgroup 2. There was no infection in subgroup 3. Peristomal infection was associated with the SI extent (P=0.01) and there was no association with PA (P=0.3). SI >5 mm presented an odds ratio of 10.5 (95% confidence interval, 1.58-68.42) for the occurrence of peristomal infection.
Conclusions:
The use of PA did not seem to reduce peristomal infection rates. However, minimal SI was significantly associated with reduction of this complication.
Insights
Minimizing skin incision (SI) during percutaneous endoscopic gastrostomy (PEG) significantly reduces peristomal infection risk. Prophylactic antibiotics (PA) did not show a similar benefit in preventing this common PEG complication.
Area of Science:
- Gastroenterology
- Surgical Procedures
- Infection Control
Background:
- Percutaneous endoscopic gastrostomy (PEG) is a common procedure.
- While generally safe, PEG carries risks, with peristomal infection being the most frequent complication.
Purpose of the Study:
- To investigate the relationship between peristomal infection rates and the size of the skin incision (SI).
- To assess the impact of prophylactic antibiotics (PA) on peristomal infection following PEG.
- To analyze outcomes in patients undergoing PEG based on SI size and PA use.
Main Methods:
- A retrospective review of 120 patients who underwent PEG.
- Patients were categorized into three groups based on skin incision size (≤5 mm or 10 mm) and prophylactic antibiotic use.
- Statistical analysis was performed to determine associations between SI, PA, and peristomal infection.
Main Results:
- Peristomal infection rates were 12.8% for SI 10 mm and 2.2% for SI ≤5 mm (without PA).
- No infections were observed in the group with SI ≤5 mm and with PA.
- A larger SI (>5 mm) was significantly associated with increased risk of peristomal infection (OR 10.5, P=0.01).
Conclusions:
- Reducing skin incision size during PEG is crucial for minimizing peristomal infection.
- Prophylactic antibiotics did not demonstrate a significant effect on reducing peristomal infection rates in this study.
- Optimal surgical technique, specifically minimal skin incision, is key to preventing PEG-related infections.
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An ostomy is a surgical procedure that creates an artificial opening from the intestines to the outside of the body, allowing for the rerouting of effluent. This opening is known as a stoma. A stoma usually protrudes above the skin surface, appearing pink or red, moist, and round, and it lacks nerve sensations.
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