Related Experiment Video
Updated: May 30, 2026

Computerized Dynamic Posturography for Postural Control Assessment in Patients with Intermittent Claudication
Published on: December 11, 2013
Orthostatic hypotension in Iranian patients with Parkinson`s disease
Ahmad Chitsaz1, Mohammad Saadatnia, Masoud Etemadifar
1Department of Neurology, Iranian Neurological Science Research Center, Isfahan, Iran.
Objective:
To prospectively investigate the prevalence and clinical relevance of orthostatic hypotension (OH) in Parkinson`s disease (PD) in Isfahan, Iran.
Methods:
We investigated 150 consecutive patients with PD (42 women, 108 men) in Al-Zahra Hospital, Isfahan, Iran from January 2002 to January 2004. Blood pressure was measured first in a supine position following a rest of at least 10 minutes, and then after 3 minutes of active standing. Data concerning the age, gender, duration of disease, and drug consumption were recorded in a questionnaire.
Results:
Orthostatic hypotension in PD is more frequent in women, patients taking a higher dose of levodopa, in higher age groups, and patients with longer duration of the disease, however, a statistically significant difference was seen in the female group and patients taking a higher dose of levodopa.
Conclusion:
Orthostatic hypotension is mainly related to PD pathology and the clinical relevance of OH to gender, age, and disease duration may be due to the natural course for progression of human autonomic dysfunction during life. Higher doses of levodopa may increase the risk of OH.
Related Concept Videos
Parkinson's Disease: Treatment
Parkinson's Disease is primarily a result of the loss of dopaminergic neurons in the substantia nigra pars compacta. The cornerstone of its...
Alterations in Blood Pressure
Hypertension (High blood pressure)
Hypertension occurs when blood pressure readings consistently exceed the normal range. It is diagnosed when systolic blood pressure (the top number, indicating pressure while the heart beats)...
Parkinson Disease l: Introduction
Parkinson's Disease: Overview
Effect of Hepatic Disease on Pharmacokinetics: Dose Adjustments Due to Hepatic Impairment
Alterations in Muscle Tone lll