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Related Concept Videos

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Cushing Syndrome II: Pathophysiology

Cortisol production is normally governed by the hypothalamic–pituitary–adrenal (HPA) axis, which maintains hormonal balance through tightly regulated feedback mechanisms. Disruption of this regulatory system is central to the development of Cushing syndrome, whether the excess cortisol originates from external medications or internal pathology. Persistent cortisol elevation alters metabolism, immune function, and endocrine signaling, producing the characteristic clinical features of the...
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Rous Sarcoma Virus (RSV) and Cancer

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Related Experiment Video

Updated: May 30, 2026

Anterior High-Resolution Optical Coherence Tomography in the Diagnosis and Therapeutic Monitoring of Ocular Surface Squamous Neoplasia
06:15

Anterior High-Resolution Optical Coherence Tomography in the Diagnosis and Therapeutic Monitoring of Ocular Surface Squamous Neoplasia

Published on: August 9, 2024

Orbital tumor presented systemic sarcoidosis.

Hafize Aktas1, Arzu Ozsoy, Figen Tokoglu

  • 1Department of Radiology, Ankara Numune Training and Education Hospital, Ankara, Turkey. Tel: +90 (312) 5084449. Fax +90 (312) 3978557.

Neurosciences (Riyadh, Saudi Arabia)
|August 23, 2011
PubMed
Summary

Sarcoidosis, a rare granulomatous disease, can present as an orbital tumor. This case highlights its unusual unilateral orbital manifestation and imaging findings.

Related Experiment Videos

Last Updated: May 30, 2026

Anterior High-Resolution Optical Coherence Tomography in the Diagnosis and Therapeutic Monitoring of Ocular Surface Squamous Neoplasia
06:15

Anterior High-Resolution Optical Coherence Tomography in the Diagnosis and Therapeutic Monitoring of Ocular Surface Squamous Neoplasia

Published on: August 9, 2024

Area of Science:

  • Ophthalmology
  • Radiology
  • Pathology

Background:

  • Sarcoidosis is a multisystemic granulomatous disease of unknown origin.
  • It commonly affects young Black adults, presenting with bilateral hilar lymphadenopathy, skin, or eyelid lesions.
  • Orbital involvement is rare, typically unilateral, often involving the lacrimal gland.

Purpose of the Study:

  • To report an isolated case of sarcoidosis initially presenting as an orbital tumor.
  • To document the computed tomography (CT) and magnetic resonance (MR) imaging appearance of orbital sarcoidosis.

Main Methods:

  • Case report of a patient with an orbital tumor.
  • Review of CT and MR imaging findings.
  • Histopathological correlation.

Main Results:

  • The patient presented with an isolated orbital mass, mimicking an orbital tumor.
  • CT and MR imaging revealed characteristic features of sarcoidosis within the orbit.
  • Diagnosis was confirmed through biopsy.

Conclusions:

  • Sarcoidosis can present as an isolated orbital tumor, a rare clinical manifestation.
  • Characteristic CT and MR imaging findings can aid in the diagnosis of orbital sarcoidosis.
  • Early diagnosis and appropriate management are crucial for patients with orbital sarcoidosis.