Related Experiment Video
Updated: May 30, 2026

An Innovative Method for Exosome Quantification and Size Measurement
Published on: January 17, 2015
Research on ultrafine particle size measurement using small amounts of data
Zhenmei Li1, Jin Shen, Wei Liu
1School of Electric and Electronic Engineering, Shandong University of Technology, Zibo 255049, China. lzm@sdut.edu.cn
Abstract:
The paper puts forward a new method of ultrafine particle size measurement using small amounts of data of a dynamic light-scattering signal, and establishes an arithmetic model of the measurement by wavelet package transform. First, through the wavelet package transform, the ultrafine particle dynamic light-scattering signals were decomposed into multifrequency bands. Then, the noise of signals of different frequency bands were removed and the power spectrum of the wavelet packet coefficients of each frequency band was calculated. Finally, the ultrafine particle size distribution information could be deduced from inversing the power spectrum. The standard polystyrene particles of 100, 300, and 400 nm were measured using this method, and the inversion results indicated that this method can effectively remove noise and improve the accuracy of particle size measurement using small amounts of data.

