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Updated: Aug 19, 2026

Bile Duct Ligation in Mice: Induction of Inflammatory Liver Injury and Fibrosis by Obstructive Cholestasis
Published on: February 10, 2015
[Spontaneous biliodigestive fistula]
M Palomar de Luis1, J I Tubía Landaberea, J L Elorza Orúe
1Hospital Ntra. Sra. de Aránzazu, San Sebastián.
Abstract:
A retrospective study was made of 23 cases of spontaneous biliodigestive fistulae collected from bile tract surgery performed in our center from 1979 to 1987, representing 1.05% of the total number of cases. The etiology was cholelithiasis in almost all cases and the most frequent connection was to the duodenum. Forty-eight percent of the cases presented as biliary ileus. In each case surgery depended on the etiology, clinical manifestations and status of the patient. The mortality was 8.7% and the morbidity 52%. Results are analyzed and a bibliographic review of the topic is offered.
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