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A Method for Selecting Structure-switching Aptamers Applied to a Colorimetric Gold Nanoparticle Assay
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A colorimetric selective sensing probe for calcium ions with tunable dynamic ranges using cytidine triphosphate

Sudeok Kim1, Juseon Kim, Na Hee Lee

  • 1Department of Chemistry, Chung-Ang University, Seoul 156-756, Republic of Korea.

Chemical Communications (Cambridge, England)
|August 23, 2011
PubMed

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Labeling DNA Probes03:31

Labeling DNA Probes

DNA probes are fragments of DNA labeled with a reporter tag to enable their detection or purification. The resulting labeled DNA probes can then hybridize to target nucleic acid sequences through complementary base-pairing, and may be used to recover or identify these regions.
Radioisotopes, fluorophores, or small molecule binding partners like biotin or digoxigenin, are the most widely used reporter tags for labeling DNA probes. These labels can be attached to the probe DNA molecule via...