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[Hemato-oncological diseases. Associated rheumatic symptoms]
1Fachklinik für Rheumatologie und Onkologie, Klinik Am Kurpark, Kurhausstrasse 9, Bad Kissingen,Germany. monika@reuss-borst.de
Zeitschrift Fur Rheumatologie
|August 23, 2011
Summary
Paraneoplastic syndromes, affecting up to 8% of cancer patients, can cause rheumatologic issues. This review details the links between rheumatic symptoms and hemato-oncological diseases for clinical relevance.
Area of Science:
- Oncology
- Rheumatology
- Immunology
Context:
- Paraneoplastic syndromes occur in up to 8% of cancer patients.
- These syndromes result from tumor secretions or immune cross-reactivity.
- Rheumatologic manifestations are among the diverse clinical presentations.
Purpose:
- To provide an overview of associations between rheumatic symptoms and hemato-oncological diseases.
- To highlight clinically relevant connections for healthcare professionals.
- To explore mechanisms including hormonal, cytokine, and immune-mediated pathways.
Summary:
- Paraneoplastic syndromes can manifest with rheumatologic symptoms, including musculoskeletal issues.
- Hematological and lymphoproliferative diseases may also present with rheumatic symptoms via direct invasion or effects on blood components.
- The article reviews these associations, emphasizing their clinical significance.
Impact:
- Enhances understanding of the interplay between cancer and rheumatic diseases.
- Aids clinicians in diagnosing and managing patients with overlapping conditions.
- Improves patient care by recognizing these complex associations.
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