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Tumor Immunotherapy01:27

Tumor Immunotherapy

Immunotherapy is a treatment that boosts or manipulates the immune system to fight diseases, including cancer. For instance, by stimulating an immune response through vaccinations against viruses that cause cancers, like hepatitis B virus and human papillomavirus, these diseases can be prevented. Nonetheless, some cancer cells can avoid the immune system due to their rapid mutation and division. The immune response to many cancers involves three phases: elimination, equilibrium, and escape.
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Asthma is a chronic respiratory condition for which new therapeutic avenues, including anti-inflammatory drugs like mast cell stabilizers and anti-IgE treatments, continue to be developed.
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Intralymphatic Immunotherapy and Vaccination in Mice
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[Specific immunotherapy and atopic dermatitis. What is new?].

N Novak1, T Werfel

  • 1Klinik und Poliklinik für Dermatologie und Allergologie, Universität Bonn, Bonn, Deutschland. Natalija.Novak@ukb.uni-bonn.de

Der Hautarzt; Zeitschrift Fur Dermatologie, Venerologie, Und Verwandte Gebiete
|August 23, 2011
PubMed
Summary

Allergen-specific immunotherapy (SIT) is a potential cure for allergies but is underused in atopic dermatitis (AD). This review explores the current data on SIT

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Area of Science:

  • Allergy and immunology
  • Dermatology
  • Immunotherapy

Context:

  • Atopic dermatitis (AD) is a common chronic inflammatory skin disease.
  • Allergen-specific immunotherapy (SIT) is the only potentially curative allergy treatment.
  • SIT is rarely used for AD due to limited controlled studies.

Purpose:

  • To summarize current data on the value of SIT in AD.
  • To provide a state-of-the-art overview of SIT for atopic dermatitis.

Summary:

  • Allergens can trigger or worsen AD in some patients.
  • Selected AD patients may benefit from SIT as an additional therapy.
  • More controlled studies are needed to establish SIT's efficacy in AD.

Impact:

  • Highlights the potential of SIT as an additional treatment for specific AD patients.
  • Addresses the gap in controlled research for SIT in atopic dermatitis.
  • Provides a current overview for clinicians and researchers on SIT for AD.