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Updated: May 30, 2026

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Guidelines for lymphoscintigraphy and F18 FDG PET scans in melanoma
Roger F Uren1, Robert Howman-Giles, David Chung
1Sydney Medical School, The University of Sydney, Sydney, NSW, Australia. ruren@usyd.edu.au
Abstract:
Melanoma has a high potential to develop metastases. Accurate staging is essential for appropriate management. Sentinel node (SN) status is a powerful prognostic factor in early stage melanoma. Staging is assisted by SN biopsy after lymphoscintigraphy to locate all true SNs prior to biopsy. PET using F18-FDG can detect metastases and is used to restage patients with AJCC Stages III and IV disease before planning surgery with curative intent.
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