Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Upper Respiratory Drugs: Antitussives, Expectorants, and Mucolytics01:23

Upper Respiratory Drugs: Antitussives, Expectorants, and Mucolytics

Respiratory symptoms, such as congestion and cough, commonly accompany respiratory tract conditions. Various medications, such as antitussives, expectorants, and mucolytics, play crucial roles in providing relief.
Antitussives include codeine, dextromethorphan (Robitussin), and benzonatate (Tessalon). Codeine and dextromethorphan exert their effects centrally by suppressing the cough reflex center in the medulla.  Benzonatate operates peripherally within the respiratory tract by anesthetizing...
COPD: Management Using Bronchodilators and Corticosteroids01:26

COPD: Management Using Bronchodilators and Corticosteroids

Chronic obstructive pulmonary isease (COPD) involves a group of progressive lung disorders characterized by persistent airflow limitation and chronic respiratory symptoms. Asthma-COPD Overlap Syndrome (ACOS), encompassing features of both asthma and Chronic obstructive pulmonary disease (COPD), is a group of progressive lung disorders that includes chronic bronchitis, emphysema, and refractory (non-reversible) asthma. ACOS leads to complex clinical presentations that combine the inflammatory...
Drugs Used in Lower Respiratory Disorders: Overview01:17

Drugs Used in Lower Respiratory Disorders: Overview

Lower respiratory tract disorders present challenges that often require skilled and nuanced approaches for effective management. Common ailments, such as asthma and chronic obstructive pulmonary disease (COPD), have prompted the development of intricate treatment strategies involving bronchodilators and anti-inflammatory drugs, each tailored to ease breathing and revitalize the lungs.
Bronchodilators, the first step of respiration enhancement, come in various forms, each with its own mechanism...
Chronic Obstructive Pulmonary Disease-V: Management01:29

Chronic Obstructive Pulmonary Disease-V: Management

Managing Chronic Obstructive Pulmonary Disease (COPD) involves a multifaceted approach to reduce symptoms, prevent exacerbations, improve overall health status, and slow disease progression. Key strategies include lifestyle modifications, pharmacotherapy, supportive therapies, and, in some cases, surgery. Here is an overview of the primary COPD management strategies:
Smoking Cessation
Drugs Used in Upper Respiratory Disorders: Overview01:16

Drugs Used in Upper Respiratory Disorders: Overview

Upper respiratory tract disorders, including viral infections and allergic rhinitis, cause significant discomfort and disrupt daily life. Managing these conditions involves a variety of drugs, such as antihistamines, intranasal steroids, decongestants, antitussives, expectorants, and mucolytics. Specific examples of drugs in each category are provided.
Antihistamines (e.g., Benadryl) block histamines from binding. Histamines are chemicals released during an allergic reaction in the body. As a...
Acute Respiratory Failure-V01:29

Acute Respiratory Failure-V

The treatment for acute respiratory failure varies based on factors like the underlying cause, overall health, and severity. A collaborative healthcare team is essential for early detection, often through arterial blood gas analysis. Identifying the cause is the primary goal, with treatment strategies adjusted for ventilation/perfusion (V/Q) mismatch, shunting, or diffusion impairment.
Ensure that patients are monitored continuously for their response to therapy, including changes in...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Paediatric bronchiectasis phenotypes and their association with clinical outcomes: development and validation in two prospective clinical cohorts.

Thorax·2026
Same author

Neutrophil-related gene expression profile is associated with future paediatric bronchiectasis exacerbations.

Journal of molecular medicine (Berlin, Germany)·2026
Same author

Improving asthma control assessment and outcomes in children with asthma using an artificial intelligence digital tool: a prospective multicentre cohort study.

ERJ open research·2026
Same author

Development of a paediatric severity score to predict outcomes of radiographic-confirmed community-acquired pneumonia in hospitalised children in Sabah, Malaysia.

Archives of disease in childhood·2026
Same author

Short and long-term effects of a play-based therapeutic exercise programme in children with non-cystic fibrosis bronchiectasis: A randomised controlled trial.

Journal of science and medicine in sport·2026
Same author

Improving the management and outcomes of preschool wheeze: protocol of a prospective multicentre cohort study.

BMJ open respiratory research·2026
Same journal

A profile on inhaled treprostinil for pulmonary hypertension.

Expert review of respiratory medicine·2026
Same journal

Effect of depemokimab on asthma control and clinical outcomes: a systematic review and meta-analysis of randomized controlled trials.

Expert review of respiratory medicine·2026
Same journal

MicroRNAs in exhaled breath condensate and plasma for diagnosis of asbestos-related interstitial lung diseases.

Expert review of respiratory medicine·2026
Same journal

Bovhyaluronidase azoximer for long-term pulmonary sequelae of COVID19: a multicenter, randomized, double-blind, placebo-controlled study.

Expert review of respiratory medicine·2026
Same journal

Role of myositis autoantibodies in diagnosing interstitial lung disease in patients with idiopathic inflammatory myopathies: a retrospective analysis.

Expert review of respiratory medicine·2026
Same journal

Delivery of care for pediatric laryngotracheal stenosis.

Expert review of respiratory medicine·2026
See all related articles

Related Experiment Video

Updated: May 30, 2026

A Traditional Chinese Medicine Characteristic Therapy for Bronchial Asthma: Moxibustion
05:56

A Traditional Chinese Medicine Characteristic Therapy for Bronchial Asthma: Moxibustion

Published on: May 12, 2023

Therapy for cough: where does it fall short?

Anne B Chang1

  • 1Child Health Division, Menzies School of Health Research, Charles Darwin University, Darwin, NT, Australia. annechang@ausdoctors.net

Expert Review of Respiratory Medicine
|August 24, 2011
PubMed
Summary
This summary is machine-generated.

Research highlights significant gaps in cough studies, including a need for better treatments and robust clinical trials. Addressing these shortfalls is crucial for improving patient quality of life and developing effective cough therapies.

More Related Videos

Establishment of a Mouse Model with Cough Hypersensitivity via Inhalation of Citric Acid
05:43

Establishment of a Mouse Model with Cough Hypersensitivity via Inhalation of Citric Acid

Published on: January 10, 2025

Related Experiment Videos

Last Updated: May 30, 2026

A Traditional Chinese Medicine Characteristic Therapy for Bronchial Asthma: Moxibustion
05:56

A Traditional Chinese Medicine Characteristic Therapy for Bronchial Asthma: Moxibustion

Published on: May 12, 2023

Establishment of a Mouse Model with Cough Hypersensitivity via Inhalation of Citric Acid
05:43

Establishment of a Mouse Model with Cough Hypersensitivity via Inhalation of Citric Acid

Published on: January 10, 2025

Area of Science:

  • Pulmonology
  • Clinical Therapeutics

Background:

  • Current cough research faces numerous challenges hindering therapeutic advancements.
  • Existing studies often lack robust methodologies and clearly defined patient cohorts.

Purpose of the Study:

  • To identify and address critical shortfalls in the study and treatment of chronic cough.
  • To outline a systematic approach for improving cough therapies and patient outcomes.

Main Methods:

  • Review of existing literature on cough studies and therapeutic interventions.
  • Analysis of identified limitations in study design, outcome measures, and etiological factor definition.

Main Results:

  • Key deficiencies include a lack of randomized controlled trials, inadequate outcome measures, and poorly defined target populations.
  • Challenges in identifying causes and predicting treatment response impede progress.
  • A need for safer, more effective cough medications is evident.

Conclusions:

  • Improving cough management requires high-quality research, better medications, and enhanced multidisciplinary guidelines.
  • A deeper understanding of human cough mechanisms is essential for developing novel therapeutics.
  • Addressing these gaps will significantly improve the lives of individuals suffering from chronic cough.