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Updated: May 30, 2026

Fertility Preservation in Patients with Severe Ovarian Dysfunction
Published on: March 25, 2021
Committee opinion no. 502: primary ovarian insufficiency in the adolescent
Abstract:
Primary ovarian insufficiency has been diagnosed in adolescents as young as age 14 years. It is estimated that approximately 1% of the female population in the United States is affected by primary ovarian insufficiency. Evaluation for all potential causes of amenorrhea, or a change from regular to irregular menses for 3 or more consecutive months, including pregnancy, polycystic ovary syndrome, hypogonadal amenorrhea, thyroid abnormalities, hyperprolactinemia, or primary ovarian insufficiency is important for young females. Understanding the unique concerns and needs associated with the diagnosis and treatment of ovarian insufficiency in adolescents is essential for the provision of quality health care for this population.
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