Stress cardiomyopathy complicated by left ventricular thrombi and cerebral infarctions in a patient with essential

Seung Hwan Hwang1, Kye Hun Kim, Hyun Ju Yoon

  • 1Department of Cardiovascular Medicine, Chonnam National University Hospital, The Research Institute of Medical Sciences, Chonnam National University, Gwangju, Korea.

Insights

Stress induced cardiomyopathy (SCMP) can have rare but serious complications like blood clots. This case highlights successful treatment of left ventricular thrombosis and cerebral infarctions in a patient with essential thrombocythemia.

Area of Science:

  • Cardiology
  • Neurology
  • Hematology

Background:

  • Stress induced cardiomyopathy (SCMP) typically has a good prognosis.
  • However, severe complications including cardiac rupture and left ventricular (LV) thrombosis can occur.
  • Essential thrombocythemia is a myeloproliferative disorder associated with increased thrombotic risk.

Observation:

  • A rare case of SCMP complicated by LV thrombosis and multiple cerebral infarctions is presented.
  • The patient had a history of essential thrombocythemia.
  • The patient presented with neurological symptoms and cardiac dysfunction.

Findings:

  • Intravenous heparin anticoagulation was initiated for LV thrombosis and cerebral infarctions.
  • Comprehensive management for heart failure and neurological deficits was administered.
  • The patient showed improvement in neurological symptoms and LV apical wall motion abnormalities.
  • Follow-up echocardiography confirmed the resolution of the LV thrombus.

Implications:

  • This case underscores the importance of considering thrombotic complications in SCMP, especially in patients with underlying prothrombotic conditions.
  • Prompt anticoagulation and multidisciplinary management can lead to favorable outcomes.
  • Further research may elucidate the specific mechanisms linking SCMP, essential thrombocythemia, and thromboembolic events.

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