[Serotonin and impulsivity (experiments on animals)]

In the current paper a role of the serotinergic system in organization of impulsive behaviour in animals was considered. The results of influence of antagonists and agonists of the different types and subtypes of 5-HT receptors (1A, B; 2A, B, C; 7) and the effects of the dorsal raphe nuclei lesions on characteristics of impulsivity related with a motor control, mechanisms of attention, reinforcement and decision making were summarized. The data on knock-out animals and the experiments with microdialysis have been also considered. There was emphasized the important role of interaction of 5-HT-, dopamine- and glutamatergic systems in mediation of impulsive behaviour.