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Updated: May 30, 2026

04:51
Pupillary Response as Assessment of Effective Seizure Induction by Electroconvulsive Therapy
Published on: April 11, 2019
[Time course changes in perfusion index and pleth variability index during electroconvulsive therapy]
Aya Tokue1, Hiroyuki Saito, Ayako Suzue
1Department of Anesthesiology, Gunma University School of Medicine, Maebahsi 371-8511.
Summary
Electroconvulsive therapy (ECT) temporarily reduces tissue perfusion, indicated by a decreased perfusion index (PI). This effect resolves within one minute post-treatment, suggesting transient impairment during psychiatric therapy.
Area of Science:
- Anesthesiology and Critical Care
- Cardiovascular Physiology
- Neuroscience
Context:
- Electroconvulsive therapy (ECT) is a vital psychiatric treatment.
- ECT can cause significant hemodynamic fluctuations and cardiac risks.
- Monitoring tissue perfusion during ECT is crucial for patient safety.
Purpose:
- To investigate the dynamic changes in perfusion index (PI) and pleth variability index (PVI) during ECT.
- To assess the time course of tissue perfusion alterations induced by ECT.
- To evaluate the utility of PI and PVI as indicators of hemodynamic changes during ECT.
Summary:
- Fifteen psychiatric patients undergoing ECT were monitored for hemodynamic variables, PI, and PVI.
- PI showed a transient decrease during ECT, returning to baseline within one minute.
- Heart rate increased transiently post-ECT, while PI was significantly lower during the procedure compared to the awake state.
Impact:
- Findings suggest transient impairment of tissue perfusion during ECT.
- Highlights the importance of continuous hemodynamic monitoring during ECT.
- PI may serve as a sensitive indicator of circulatory changes in ECT patients.

