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The carboxy terminus of human immunodeficiency virus type 1 gp160 limits its proteolytic processing and transport in

O K Haffar1, G R Nakamura, P W Berman

  • 1Department of Developmental Biology, Genetech Inc., South San Francisco, California 94080.

Journal of Virology
|June 1, 1990
PubMed

Mutagenesis of the transmembrane domain and cytoplasmic tail of human immunodeficiency virus type 1 envelope glycoprotein gp160 revealed that its intracellular transport and processing in transfected cell lines were modulated by a functional domain included in the carboxy-terminal sequence consisting of residues 751 to 856.

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