Related Experiment Video
Updated: May 30, 2026

Refined Murine Model of Idiopathic Pulmonary Fibrosis
Published on: June 17, 2025
High resolution CT and histological findings in idiopathic pleuroparenchymal fibroelastosis: features and
Sara Piciucchi1, Sara Tomassetti, Gianluca Casoni
1Department of Radiology, Scientific Institute for study and treatment of Cancer-IRST; Via Piero Maroncelli 40-42; 47014; Meldola-Forlì; Italy. s.piciucchi@alice.it
Abstract:
Idiopathic pleuroparenchymal fibroelastosis (IPPFE) is a recently described clinical-pathologic entity characterized by pleural and subpleural parenchymal fibrosis, mainly in the upper lobes. As this disease is extremely rare (only 7 cases have been described in the literature to date) poorly defined cases of IPPFE can go unrecognized.The clinical course of disease is progressive and prognosis is poor, with no therapeutic options other than lung transplantation currently available, yet. The aim of this report is to describe two further cases of this rare disease, reviewing CT, clinical and histological features.
Related Concept Videos
Chronic Obstructive Pulmonary Disease II: Emphysema
Pleural Effusion I: Introduction
There are two main types of pleural effusion: transudative and exudative. They are differentiated using Light's criteria,...
Pericarditis II: Clinical Features and Diagnostic Tests
Chronic Obstructive Pulmonary Disease IV: Clinical Manifestations
Chronic Obstructive Pulmonary Disease III: Chronic Bronchitis Features
Chronic Obstructive Pulmonary Disease-IV: Assessement and Diagnostic Studies
Medical History
