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A comparative gene expression database for invertebrates
Mattias Ormestad1, Mark Q Martindale, Eric Röttinger
1Kewalo Marine Laboratory, PBRC, University of Hawaii at Manoa, 41, Ahui Street, Honolulu, 96734, HI, USA. rottinge@hawaii.edu.
Evodevo
|August 25, 2011
Summary
A new database integrates diverse invertebrate gene expression data for evolutionary developmental biology (Evo-Devo) research. This tool facilitates cross-species comparisons, aiding in the identification of gene regulatory networks.
Area of Science:
- Evolutionary Developmental Biology (Evo-Devo)
- Bioinformatics
- Genomics
Background:
- Emergence of numerous 'exotic' animal models due to advances in sequencing technologies.
- Challenges in comparing gene expression patterns across diverse species and datasets.
- Growing need for organized, publicly accessible gene expression data.
Purpose of the Study:
- To develop a web-based comparative gene expression database for invertebrates.
- To enable homogenous storage and handling of gene expression patterns.
- To facilitate both species-specific and cross-species gene expression comparisons.
Main Methods:
- Development of a novel web-based database.
- Implementation of query functionalities by gene name, developmental stage, and expression domains.
- Integration of diverse invertebrate gene expression data.
Main Results:
- Creation of the first web-based comparative gene expression database for invertebrates.
- Database allows querying by gene, developmental stage, and expression domains.
- Facilitates retrieval and analysis of gene expression patterns.
Conclusions:
- Provides a unique tool for the Evo-Devo research community.
- Enables within- and among-species gene expression pattern comparisons.
- Aids in identifying syn-expression groups for gene regulatory network projects.
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