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Related Concept Videos

Acute Kidney Injury II: Pathophysiology01:29

Acute Kidney Injury II: Pathophysiology

Acute kidney injury (AKI) causes are categorized into three primary categories based on the location of the injury: prerenal, intrarenal (or intrinsic), and postrenal causes. This classification guides clinical management and illustrates how different pathways can impair kidney function.Etiology and Pathophysiology of Acute Kidney Injury1. Prerenal causesEtiology: Prerenal Acute Kidney Injury, the most common type, occurs when reduced blood flow to the kidneys decreases filtration capacity...
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Nephrogenic adenoma in the augmented bladder.

Ethan I Franke1, Rosalia Misseri, Mark P Cain

  • 1Division of Pediatric Urology and Pathology, Riley Hospital for Children, Indiana University Medical Center, Indianapolis, Indiana, USA.

The Journal of Urology
|August 25, 2011
PubMed
Summary
This summary is machine-generated.

Nephrogenic adenoma is not rare in augmented bladders, often appearing asymptomatically. These lesions may stem from chronic catheterization injury and can recur, necessitating surveillance.

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Area of Science:

  • Urology
  • Pediatric Surgery
  • Pathology

Background:

  • Nephrogenic adenoma is a benign urothelial lesion.
  • Known risk factors include trauma, inflammation, immunosuppression, and radiation.

Purpose of the Study:

  • To characterize nephrogenic adenoma in pediatric augmented bladders.
  • To investigate its presentation, recurrence, and risk factors in this specific population.

Main Methods:

  • Retrospective review of patients diagnosed with nephrogenic adenoma between January 2000 and March 2010.
  • Focus on patients with prior bladder augmentation, analyzing pathological characteristics, cystoscopic findings, and recurrence patterns.

Main Results:

  • Ten patients with ileal bladder augmentation and nephrogenic adenoma were identified.
  • The mean time to diagnosis was 9.2 years post-augmentation.
  • Lesions were often found at sites prone to catheterization injury, and 2 of 6 patients who returned for surveillance experienced recurrence.

Conclusions:

  • Nephrogenic adenoma is not uncommon in augmented bladders and can be asymptomatic.
  • Development may be linked to chronic catheterization-related injury.
  • Recurrence of lesions is a notable concern.