Related Experiment Video
Updated: May 30, 2026
Biological Compatibility Profile on Biomaterials for Bone Regeneration
Published on: November 16, 2018
Coverage of gingival recession defects using acellular dermal matrix allograft with or without beta-tricalcium
Nobuki Okubo1, Takahisa Fujita, Yoshihito Ishii
1Department of Periodontology, Tokyo Dental College, 1-2-2, Masago Mihama-ku, Chiba, 261-8502, Japan. ookubonobuki@tdc.ac.jp
Abstract:
The aim of this study was to investigate the effect of beta-tricalcium phosphate (β-TCP) particles in combination with acellular dermal matrix (ADM) allograft in gingival recession. Experimental gingival recession defects were created in beagle dogs and randomly assigned to one of the following groups: ADM, ADM + β-TCP, or coronally positioned flap (CPF; control). Tissues were histologically examined at 4, 8, or 16 weeks following treatment. A greater thickness of gingiva was observed at the sites treated in both the ADM + β-TCP and ADM groups than in the CPF group. The ADM + β-TCP group showed a statistically significant increase in both new bone and cementum formations compared to the ADM group. The results suggest that the combination of β-TCP and ADM is more effective in promoting new bone and cementum formations than ADM graft alone.
